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Treatments differ based on whether your diverticulitis is considered complicated or uncomplicated: Complicated: You have diverticula with inflammation that is more severe or spread out, as well as potentially abscesses (pockets of pus), perforation (intestine wall has torn), obstruction (blockage in the intestine), peritonitis (infection in the inner lining of your abdomen), ascites (fluid build-up in your abdomen), and other complications

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For instance, GF mice have modified gut shape, characterized by diminished total intestinal mass, expanded cecum, shorter and thinner villi, and depleted mucus layers, decreased epithelial cell renewal, and impaired intestinal motility 12

Calcium mobilization assay Calcium mobilization assay to measure GHSR signaling was carried out in HEK-293T cells cultured in DMEM supplemented with 10% (vol/vol) FBS (Fisher Scientific)